Rudeness is a serious shortcoming.

粗鲁无礼是一个严重的缺点。

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Kosaku Shima of Hatsushiba Goyo Holdings has only one serious shortcoming: he is not a real person, but a manga, or cartoon, character (see article).

初芝电产株式会社的课长岛耕作只有一个致命缺点：他不是真人，而是个漫画人物。

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The modest pressure promotes the graduate to keep continuous energy and focus on scientific research, but too much pressure will lead to mental problem and serious moral shortcoming.

适度的压力能使研究生集中精力于科学研究，保持旺盛的科研意志，但过大的科研压力不仅使研究生心理受到损害，而且可能导致严重的学术腐败。

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Given the extent to which business is being done on an international scale, this is a serious shortcoming.

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Close observers of the government suggest that the limited accountability of the cabinet, exacerbated by personal animosity among ministers, has become a serious shortcoming.

ECONOMIST: Egypt��s waiting game

That proportion is falling, but not quickly enough: Our analysis shows that about a third of all apps we have evaluated still have at least one serious shortcoming.

FORBES: Online Publications Need Better Apps